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Barrows, Isabel (17 April 1845–25 October 1913), ophthalmologist, stenographer, and reformer, was born Katharine Isabel Hayes in Irasburg, Vermont, the daughter of Scottish immigrants Henry Hayes, a physician, and Anna Gibb, a schoolteacher. The family moved to Hartland and then Derry, New Hampshire, where Isabel Hayes graduated from Adams Academy. In 1863 she married William Wilberforce Chapin, a Congregational minister. The following year the couple traveled to India for a missionary assignment. Less than a year after arriving in India, William Chapin died of diphtheria. Six months later Isabel Chapin returned to the United States. She moved to Dansville, New York, where she worked as a bath assistant at a water-cure sanatorium....

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Hepburn, James Curtis (13 March 1815–21 September 1911), medical missionary, oculist, and lexicographer, was born in Milton, Pennsylvania, the son of Samuel Hepburn, a lawyer, and Ann Clay, the daughter of the Reverend Slator Clay. Hepburn received his early education at home and at the Milton Academy. At the age of fourteen he matriculated as a junior in Princeton College, from which he graduated in 1832. He began his medical studies with Dr. Samuel Pollack of Milton, Pennsylvania, and then attended the University of Pennsylvania Medical School, from which he graduated with an M.D. in 1836. In 1835 he was awarded an A.M. by Princeton College....