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MacNider, William De Berniere (25 June 1881–31 May 1951), physician and medical educator, was born in Chapel Hill, North Carolina, the son of Virginius St. Clair MacNider, a physician, and Sophia Beatty Mallett. MacNider was keenly interested in natural history and science during his childhood, and the university environment at Chapel Hill undoubtedly strengthened his desire for a career in the biological sciences. After attending public schools in Chapel Hill, he enrolled at the University of North Carolina in 1898. His father and grandfather were both physicians, and their influence probably contributed to his choice of a medical career; while an undergraduate, he resolved to become a medical researcher. His abilities were soon recognized by the faculty, and he was hired during his graduate study years as an assistant in biology from 1899 to 1900, as assistant in anatomy from 1900 to 1902, and as assistant in clinical diagnosis from 1902 until 1905. MacNider graduated in 1903 with the first class of the University of North Carolina Medical School to receive the M.D. degree. He subsequently received additional research and clinical training at the University of Chicago and at Case Western Reserve University in Cleveland. During these formative years MacNider benefited significantly from the mentorship of such prominent biologists and medical scientists as ...